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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CASP1 — CD4

Text-mined interactions from Literome

Ruiz et al., Clin Immunol 2001 : These findings demonstrate that intracellular caspase-1- and -3-like enzyme activity increases in both CD4 ( + ) and CD8 ( + ) alloreactive T cells as the primary response to allostimulatory cells progresses
Suresh et al., J Immunol 2002 : PF inhibits activation mediated loss of superantigen-reactive CD4 as well as CD8 T cells in vivo without significantly affecting their activation, and inhibits activation induced death and caspase induction in stimulated CD4 as well as CD8 T cells in vitro without preventing the induction of activation markers
Neumann et al., Int J Cancer 2004 (Breast Neoplasms) : The CD4+ mediated response against p45-59 and its DR restriction was demonstrated by inhibition with anti-CD4 and HLA-DR antibodies, respectively, and by blocking experiments using HLA-specific antibodies
Mukherjee et al., J Leukoc Biol 2005 : The enhanced CD4 ( + ) T cell death with a suppressive dose of Con A is dependent on excess H ( 2 ) O ( 2 ) and nitric oxide but is independent of Fas and caspase activity
Ichinohe et al., J Exp Med 2009 (Orthomyxoviridae Infections) : Although NLRP3 was required for inflammasome activation in certain cell types, CD4 and CD8 T cell responses, as well as mucosal IgA secretion and systemic IgG responses, required ASC and caspase-1 but not NLRP3
Bagchi et al., J Clin Immunol 2010 (Dysentery, Bacillary) : It is assumed that the role of caspase-1 in inducing the CD4+ T cell activity increased with IL-18 rather than CD8+ suppressor cell activity