◀ Back to CASP1

CASP1 — MYLIP

Text-mined interactions from Literome

Levrand et al., Free Radic Biol Med 2006 (Myocardial Ischemia) : In vivo, MIR triggered myocardial oxidative stress ( malondialdehyde generation ), nitrotyrosine formation, neutrophil accumulation, and the cleavage of caspase-3 and PARP, indicating ongoing myocardial apoptosis
Xu et al., J Cell Sci 2007 : By contrast, miR-133 repressed caspase-9 expression at both the protein and mRNA levels ... Post-transcriptional repression of HSP60 and HSP70 by miR-1 and of caspase-9 by miR-133 contributes significantly to their opposing actions
Corsten et al., Cancer Res 2007 (Brain Neoplasms...) : With the use of locked nucleic acid ( LNA ) -antimiR-21 oligonucleotides, bimodal imaging vectors, and neural precursor cells (NPC) expressing a secretable variant of the cytotoxic agent tumor necrosis factor related apoptosis inducing ligand ( S-TRAIL ), we show that the combined suppression of miR-21 and NPC-S-TRAIL leads to a synergistic increase in caspase activity and significantly decreased cell viability in human glioma cells in vitro
Ferracin et al., Molecular cancer 2010 (Leukemia, Lymphocytic, Chronic, B-Cell...) : Importantly, inhibition of miR-21 and miR-222 by anti-miRNA oligonucleotides induced a significant increase in caspase activity in fludarabine treated p53-mutant MEG-01 cells, suggesting that miR-21 and miR-222 up-regulation may be involved in the establishment of fludarabine resistance
Zhou et al., Oncol Rep 2010 (Brain Neoplasms...) : Moreover, reduction of miR-21 activated caspase 9 and 3, which may be mediated by modulating multiple potential target genes, such as TIMP3
Dar et al., J Biol Chem 2011 (Melanoma...) : miR-205 overexpression resulted in induction of apoptosis, as evidenced by increased cleaved caspase-3 , poly- ( ADP-ribose ) polymerase, and cytochrome c release
Feng et al., Nucleic Acids Res 2011 (Lung Neoplasms) : Both caspase-7 and the PARP protein were activated by the overexpression of miR-192 , thus suggesting that miR-192 induces cell apoptosis through the caspase pathway
Fang et al., Apoptosis 2012 (Myocardial Ischemia) : This study first showed that miR-378 inhibited caspase-3 expression and attenuated ischemic injury in cardiomyocytes
Fitzgerald et al., Fertil Steril 2012 (Leiomyoma...) : Loss of miR-21 also increased cleavage of caspase-3 ( apoptosis marker ) and increased phosphorylation of elongation factor-2 ( marker of reduced translation ) in both cell lines
Bao et al., Apoptosis 2013 (Myocardial Infarction...) : We found that cleaved caspase3 expression was up-regulated by miR-384-5p and down-regulated by miR-384-5p inhibitor suggesting that apoptosis pathway was regulated by miR-384-5p
Rong et al., BMC cancer 2013 (Carcinoma, Hepatocellular...) : The effects of miR-221 on cell growth, cell cycle, caspase activity and apoptosis were also investigated by spectrophotometry, fluorimetry, fluorescence microscopy and flow cytometry, respectively
Li et al., Biochem J 2013 (Airway Remodeling...) : Expression of exogenous miR-138 suppressed PASMC apoptosis, prevented caspase activation and disrupted Bcl-2 signalling
Nakano et al., Int J Oncol 2013 : Overexpression of miR-193a and miR-193b induced an activation of caspase 3/7, and resulted in apoptotic cell death in A2780 cells
Wang et al., Cell death & disease 2013 : miR-874 regulates myocardial necrosis by targeting caspase-8