Gene interactions and pathways from curated databases and text-mining

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HLA-DRB1 — TNFRSF10C

Text-mined interactions from Literome

Liu et al., Exp Hematol 2001 (Multiple Myeloma) : Myeloma cells resistant to Ad-p53 had high levels of DR4/DR5 and high levels of DcR1 and treatment with Ad-p53 did not reduce the expression of DcR1
Bild et al., Oncogene 2002 : We show that by preventing DR4 and DR5 activation through expression of decoy receptor 1 (DcR1) and dominant negative FADD, we inhibit MEKK1 induced apoptosis
Mérino et al., Mol Cell Biol 2006 : In addition, DcR1 and DcR2 inhibit DR4- and DR5 mediated, TRAIL induced apoptosis and we demonstrate here that this occurs through distinct mechanisms