◀ Back to STAT1

STAT1 — TCF15

Text-mined interactions from Literome

Federico et al., Blood 2001 (Acquired Immunodeficiency Syndrome) : Nef dependent STAT1 activation is followed by increased expression of both STAT1 and interferon regulatory factor-1, a transcription factor transcriptionally regulated by STAT1 activation
Ghoreschi et al., J Mol Med (Berl) 2003 (Psoriasis) : STAT1 activation by IFN-gamma is followed by T-bet activation, a master transcription factor for Th1 lymphocytes
Plumlee et al., Virology journal 2005 : Phosphorylation of Stat1 on a conserved serine amino acid at position 727 ( S727 ), results in maximal transcriptional activity of the ISGF-3 transcription factor complex 15
Torrero et al., Cancer Res 2006 (Carcinoma, Squamous Cell) : Signal transducer and activator of transcription 1 ( Stat1 ) is considered a key transcription factor that inhibits tumorigenesis, and Stat1 activation in the host is required for interleukin-12 (IL-12) mediated generation of CTL activity
Rani et al., J Interferon Cytokine Res 2007 : TRAIL was not induced by IFN-beta in mutant cell lines U2A, U3A, U4A, U5A, and U6A, which lack, respectively, IFN regulatory factor-9 (IRF-9), Stat1 , Jak1, IFNAR-2.2, and Stat2, indicating transcription factor IFN stimulated gene factor 3 ( ISGF3 ) was essential for the induction of this gene
Cantrell et al., Immunobiology 2010 (Melanoma, Experimental) : Activation of both cell types is associated with the induction of the MAP kinase pathway, the phosphorylation of STAT1 , STAT5 and AKT and with transcription factor NF-kappaB activation in vitro and in vivo