◀ Back to RELA
PMPCB — RELA
Text-mined interactions from Literome
Helenius et al., Antioxid Redox Signal 2001
:
The up-regulation of constitutive nuclear NF-kappa B binding activity and increased levels of nuclear
p52 and p65 proteins might
affect the expression of some
NF-kappa B target genes in the aging liver
Monaco et al., Proc Natl Acad Sci U S A 2004
(Arteriosclerosis...) :
We found that
NF-kappa B is activated in these cells and that this activity
involves p65, p50, and c-Rel but not
p52 or RelB
Iwamoto et al., Tohoku J Exp Med 2005
(Body Weight...) :
Supershift assays with specific antibodies revealed that p50, but not
p52 , p65, Rel B, or c-Rel, may be
involved in the activation of
NF-kappaB , though the component primarily responsible for the increase could not be determined
Eisner et al., FEBS Lett 2006
:
Supershift analysis revealed that p65 and RelB ( but not p50,
p52 or cRel ) were
involved in the binding of
NFkappaB to DNA
Nadiminty et al., Cancer Res 2010
(Disease Progression...) :
Comparison of the relative effects of p52 and p65 (RelA) showed that
p52 , but not p65, could
activate the AR. Collectively, these findings, together with previous reports that the levels of
NF-kappaB2/p52 are elevated in prostate cancer cells and that active NF-kappaB2/p52 promotes prostate cancer cell growth in vitro and in vivo, suggest that NF-kappaB2/p52 may play a critical role in the progression of castration-resistant prostate cancer
Li et al., Nat Immunol 2010
:
Because of low expression of the transcription factor RelB in untreated macrophages, high
p52 expression
repressed basal transcription of both canonical and noncanonical
NF-kappaB target genes
Altaf et al., Inflammopharmacology 2013
:
Only
RelA and c-rel ( p < 0.01 ) were
increased by one diamond nanoparticle and
p52 and c-rel ( p < 0.01 ) by another nanoparticulate diamond