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DISC1 — HMOX1

Text-mined interactions from Literome

Kim et al., Autophagy 2008 (Necrosis...) : Adenoviral mediated expression of HO-1 inhibited DISC formation and caspase-3/9 activation in CSE treated epithelial cells, diminished the expression of Beclin 1, and partially inhibited the processing of LC3B-I to LC3B-II
Kim et al., Shock 2013 (Reperfusion Injury) : Our findings suggest that the cytoprotective effects of HO-1 are mediated by suppression of TNF/TNFR1 mediated apoptotic signaling, specifically by modulating apoptotic DISC formation and mitochondrial TNFR1 translocation during hepatic I/R