Gene interactions and pathways from curated databases and text-mining

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E2F1 — HDAC2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Boutillier et al., J Neurochem 2003 : Taken together, our results suggest that, in neuroprotective conditions, histone deacetylase activity allows a constitutive repression of the e2f-1 gene in mature neurones in order to ensure survival
Zhang et al., Nucleic Acids Res 2005 : The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription ... Functionally, Sin3A enhanced the ability of Ebp1 to repress transcription of androgen receptor (AR) and E2F1 regulated genes
Duan et al., Prostate 2013 (Prostatic Neoplasms) : While androgen suppresses EZH2 in CRPC cells, in LNCaP cells, physiological concentrations of androgen stimulate expression of PRC2 genes ( EZH2, SUZ12, and EED ), which is mediated by androgen induced ANCCA and involves E2F and histone H3K4me3 methylase MLL1 complex