Gene interactions and pathways from curated databases and text-mining

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CIB1 — FOXO3

Text-mined interactions from Literome

Essaghir et al., J Biol Chem 2009 : Conversely, ectopic FOXO3 activation blocked the proliferation of fibroblasts and induced the expression of FOXO1, FOXO4, and p27-KIP1
Chen et al., PloS one 2010 (Prostatic Neoplasms) : The inhibition of PI3K/AKT pathway induced FOXO transcriptional activity resulting in induction of Bim, TRAIL, p27/KIP1 , DR4 and DR5, and inhibition of cyclin D1
Qi et al., BMC cancer 2011 (Colonic Neoplasms) : Thus, the FOXO3-p53 ( mut ) complex leads to elevated p27kip1 expression and promotes cell cycle arrest
Qi et al., J Biol Chem 2013 (Colonic Neoplasms) : In parallel, LD-dependent loss of FOXO3 led to its dissociation from the promoter and decreased expression of the cell cycle inhibitor p27kip1