Tassi et al., Eur J Immunol 2009
:
Dectin-1 required PLCgamma2 to activate MAPK, AP-1 and NF-kappaB, which induce cytokine gene expression
Galán-Díez et al., Infect Immun 2010
:
At the molecular level, the disruption of CEK1 resulted in altered spleen tyrosine kinase (Syk), Raf-1, and ERK1/2 activations together with IkappaB degradation on hDCs and increased dectin-1 dependent activator protein 1 (AP-1) activation on transfected cells