Gene interactions and pathways from curated databases and text-mining

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CSN2 — IL4

Text-mined interactions from Literome

Singh et al., FEMS Immunol Med Microbiol 2009 (Hypersensitivity, Immediate...) : Without hydrolyzation, casein reduced the production of interleukin-4 , which indicates that probiotics modify the structure of potentially harmful antigens and thereby alter the mode of their immunogenicity
Sütas et al., Scand J Immunol 1996 (Dermatitis, Atopic) : Purified casein up-regulated the interleukin-4 and interferon-gamma production, P = 0.008 and P = 0.008, respectively ... Conversely, Lactobacillus GG-degraded casein down-regulated the interleukin-4 production, P = 0.003, with no effect on interferon-gamma