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Zhu et al., Am J Obstet Gynecol 2010
:
The
miR-152 repressed
HLA-G expression but exerted no effect on JEG-3 cell invasion, and overexpression of miR-152 led to increased NK cell mediated cytolysis in JEG-3 cells
Manaster et al., PloS one 2012
:
Here we demonstrate that
miR-148a and miR-152 down-regulate HLA-G expression by binding its 3'UTR and that this down-regulation of
HLA-G affects LILRB1 recognition and consequently, abolishes the LILRB1 mediated inhibition of NK cell killing