◀ Back to CDKN2A

CDKN2A — PDLIM7

Text-mined interactions from Literome

Ohtani et al., J Cell Biol 2003 : Unlike other DNA tumor virus oncoproteins, which possess immortalizing activity, LMP1 does not bind to retinoblastoma tumor suppressor protein, but instead blocks the expression of p16INK4a tumor suppressor gene ... However, it has been unclear how LMP1 represses the p16INK4a gene expression
Ding et al., J Med Virol 2007 : In this study, it was indicated that LMP1 inhibited p16(INK4A) expression, promoted phosphorylation of p105 Rb and upregulated E2F1 expression as well as transactivation, and overexpression of E2F1 alone was sufficient to upregulate telomerase activity