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MMP13 — POLDIP2

Text-mined interactions from Literome

Boström et al., Int J Cancer 2000 (Carcinoma, Transitional Cell...) : Retinoids and a selective p38 inhibitor, SB203580, potently inhibited MMP-13 mRNA expression
Zeliadt et al., Toxicol Appl Pharmacol 2003 : Diverse stimuli require JNK and p38 to increase MMP-13 gene expression, however ... Surprisingly, palytoxin does not require JNK and p38 to increase MMP-13 gene expression
Fan et al., Rheumatol Int 2006 : Our data suggest that ERK and NFkB pathways are particularly important for IL-1beta regulating collagen type II and MMP-1 and -13 expression and that p38 , but not JNK is additionally involved in MMP-1 and -13 induction
Pei et al., Osteoarthritis Cartilage 2006 (Chondrosarcoma) : The possible involvement of the Runx2 pathway in mediating p38 effects on MMP-13 expression was analyzed using promoter-reporter assays, ELISA and immunoprecipitation analyses
Junttila et al., Oncogene 2007 (Carcinoma, Squamous Cell...) : Inhibition of endogenous p38alpha or p38delta activity by adenoviral delivery of corresponding dominant negative p38 isoforms potently reduced MMP-13 and MMP-1 expressions, and suppressed the invasion of HNSCC cells through collagen
Long et al., Osteoarthritis Cartilage 2010 (Inflammation...) : Inhibition of both p38alpha and p38gamma with BIRB796 resulted in less inhibition of MMP-13 production in response to IL-1beta or FN-f than did inhibition of only p38alpha with SB203580
Meephansan et al., Clin Exp Dermatol 2012 (Carcinoma, Squamous Cell...) : Induction of MMP-9 by TNF-a was suppressed by an extracellular signal regulated kinase ( ERK ) inhibitor but not by a p38 inhibitor, whereas induction of MMP-13 was inhibited by a p38 inhibitor but not by an ERK inhibitor