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IL17A — PIK3R1

Text-mined interactions from Literome

Cho et al., Immunol Lett 2007 (Arthritis, Rheumatoid) : Moreover PI3K/Akt inhibitor, NF-kappaB inhibitor, and FK506 significantly inhibited IL-15 induced IL-17 production in CD4+ T cells
Kim et al., J Immunol 2007 (Asthma...) : Our results also showed that PI3K inhibitors or AdPTEN down-regulated a transcription factor, NF-kappaB activity, and BAY 11-7085 substantially reduced the increased levels of IL-17 after TDI inhalation
Gislette et al., TheScientificWorldJournal 2010 (Neoplasms...) : IL-17 could activate Src/PI3K , MAPK, Stat3, and PKC, resulting in carcinogenesis
Harris et al., Eur J Immunol 2012 : In this study, we reveal a novel role for PI3K? in the regulation of the pro-inflammatory cytokine IL-17 ... Loss of PI3K? or expression of a catalytically inactive mutant of PI3K? in mice led to increased IL-17 production both in vitro and in vivo in response to various stimuli
Roller et al., J Immunol 2012 (Dermatitis...) : We also show that PI3Kd and PI3K? inhibitors reduced IFN-? production by human TCR?d T cells and IL-17 and IFN-? production by PBMCs from psoriatic or healthy donors
Liu et al., Autophagy 2013 (Pulmonary Fibrosis) : In response to IL17A stimulation, PI3K was activated and resulted in phosphorylation of GSK3B at Ser9, which subsequently attenuated the interaction of GSK3B with BCL2