Gene interactions and pathways from curated databases and text-mining

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BMP1 — TNF

Text-mined interactions from Literome

Kaneki et al., J Biol Chem 2006 : TNF inhibited the expression of bone morphogenetic protein and transforming growth factor-beta signaling reporter constructs, and the inhibition of each was blocked by Smurf1 siRNA and Smurf2 siRNA, respectively
Paterson et al., J Psychopharmacol 2006 : Antipsychotic drugs and PCP significantly reduced the levels of TNF in the prefrontal cortex compared to vehicle treated animals, whilst other cytokines remained unchanged
He et al., Zhonghua Wai Ke Za Zhi 2006 : To study the feasibility of osteogenic phenotype expression by human skin fibroblasts induced in polyglycolic acid ( PGA ) foams and the effect of tumor necrosis factor-alpha (TNF-alpha) on the expression of bone morphogenetic protein ( BMP ) receptors
Punturieri et al., J Immunol 2006 : AMphi derived from STAT1-deficient mice did not demonstrate increased production of TNF-alpha in response to PCP plus IFN-beta
Singhatanadgit et al., Int J Biochem Cell Biol 2006 : Bone morphogenetic protein receptors and bone morphogenetic protein signaling are controlled by tumor necrosis factor-alpha in human bone cells
Hong et al., Immunology 2009 : In addition, BMP-6 induced expression of pro-inflammatory inducible nitric oxide synthase (iNOS) and the cytokine tumour necrosis factor (TNF)-alpha
Yamazaki et al., J Biol Chem 2009 : These results suggest that TNFalpha inhibits BMP signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB
Pacios et al., FASEB J 2012 (Diabetes Mellitus, Experimental...) : TNF inhibition in diabetic animals also reduced apoptosis, increased proliferation of bone lining cells, and increased mRNA levels of FGF-2, TGFß-1, BMP-2 , and BMP-6
Kim et al., Food Chem Toxicol 2012 (MAP Kinase Signaling System) : PCP increased the production of nitric oxide ( NO ) and the gene expression of IL-1ß, IL-6, and TNF-a in RAW 264.7 cells