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IL13 — TNFRSF11B

Text-mined interactions from Literome

Lawrie et al., Am J Pathol 2008 (Hypertension, Pulmonary) : Additionally, both 5-HT and interleukin-1 also increased OPG secretion
Stein et al., J Bone Miner Res 2008 : Interleukin-4 and interleukin-13 stimulate the osteoclast inhibitor osteoprotegerin by human endothelial cells through the STAT6 pathway ... IL-4 and IL-13 induced OPG mRNA levels and protein secretion in HUVEC by up to 4-fold in a dose- and time dependent fashion ( maximum effect after 48 h and at 10 ng/ml ) ... In summary, IL-4 and IL-13 induced OPG expression through activation of STAT6 in endothelial cells, and HUVEC derived OPG is an IL-4/IL-13 induced inhibitor of osteoclastic resorption