Song et al., AIDS Res Hum Retroviruses 2009
(HIV Infections) :
Therefore, although CD8 ( + ) T cells can be directly activated by TLR7 , accessory cells must play an essential role in the activation of effective functions such as IFN-gamma production
Heidegger et al., J Immunol 2013
(Salmonella Infections) :
We further show that this downregulation is dependent on TLR signaling, and that the TLR activated naive CD8 ( + ) T cells are blocked from entering GALT