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BDNF — IGF1

Text-mined interactions from Literome

Pfenninger et al., J Cell Sci 2003 : Because both BDNF and IGF-1 are known to enhance neurite growth, but BDNF did not stimulate membrane expansion at the growth cone, we studied the effect of BDNF on the IGF-1 receptor
McCusker et al., J Neuroimmunol 2006 : Insulin-like growth factor-I enhances the biological activity of brain derived neurotrophic factor on cerebrocortical neurons ... This IGF-I induced increase in BDNF responsiveness describes a new interaction between these peptides in the brain
Park et al., Journal of neuroinflammation 2011 (Body Weight...) : Moreover, IGF-I increased expression of BDNF
Paslakis et al., Med Hypotheses 2012 : In fact, it has been suggested that the increase in hippocampal BDNF following antidepressant treatment or physical exercise in animal models is IGF-I dependent and that antidepressant treatment increases IGF-I in human cerebrospinal fluid (CSF)