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HDAC1 — REST

Pathways - manually collected, often from reviews:

• Reactome Reaction: HDAC1 → REST (indirect_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: HDAC1 — REST (direct interaction, pull down) Gocke et al., PloS one 2008
• IRef Biogrid Interaction: HDAC1 — REST (physical association, affinity chromatography technology) Huang et al., Nat Neurosci 1999*

Text-mined interactions from Literome

Roopra et al., Mol Cell Biol 2000 : Furthermore, we show that REST/NRSF binds mammalian SIN3A and HDAC-2 and requires histone deacetylase activity to repress neuronal gene transcription in both nonneuronal and neuronal cell lines
Battaglioli et al., J Biol Chem 2002 : Previous studies have shown that REST mediated repression requires histone deacetylase activity and that recruitment of deacetylases is mediated by two co-repressors, Sin3A and CoREST