Gene interactions and pathways from curated databases and text-mining

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CD46 — RELA

Text-mined interactions from Literome

Nanji et al., Am J Physiol Gastrointest Liver Physiol 2001 (Endotoxemia...) : We analyzed liver histopathology, lipid peroxidation, cytochrome P-450 (CYP)2E1 activity, nonheme iron, endotoxin, nuclear factor-kappa B (NF-kappa B) activation , and mRNA levels of cyclooxygenase-1 (COX-1) and COX-2, tumor necrosis factor-alpha (TNF-alpha), monocyte chemotactic protein-1 (MCP-1) , and macrophage inflammatory protein-2 ( MIP-2 )
Carpenter et al., BMC infectious diseases 2002 (Lung Neoplasms) : In this study, we examined the NF-kappaB mediated effects of RSV and the proinflammatory cytokine TNFalpha on the induction of IL-8, MCP-1 and RANTES chemokine gene expression in A549 epithelial cells
Massberg et al., Thromb Res 2003 (Inflammation) : Platelet mediated MCP secretion by SMCs involved the activation and nuclear translocation of the transcription factor nuclear factor-kappaB (NF-kappaB)
Zheng et al., J Huazhong Univ Sci Technolog Med Sci 2004 (Pancreatitis) : The activity of NF-kappaB in pancreatic acinar cells was significantly increased ( P < 0.01 ) after treated with M3 cholinergic receptor agonist ( 10 ( -3 ) mol/L carbachol ) in vitro for 30 min. Either M3 cholinergic receptor antagonist ( 10 ( -5 ) mol/L atropine ) or NF-kappaB inhibitor ( 10 ( -2 ) mol/L PDTC ) could obviously inhibit the activation of NF-kappaB and the chemokine MOB-1, MCP-1 mRNA expression induced by carbachol ( P < 0.05 )
McCord et al., Infect Immun 2005 : However, MCP-1 production was dependent on NF-kappaB activity
Jang et al., Life Sci 2006 : In this study, the effects of scoparone on the expression of interleukin-8 (IL-8) and monocyte chemotactic protein-1 (MCP-1) and activation of nuclear factor-kappaB (NF-kappaB) were examined in U937 human monocytes activated with phorbol 12-myristate 13-acetate ( PMA )
Shimada et al., FEBS Lett 2010 : In summary, MCP-1 production was partly regulated by ROCK acting upstream of p38 and JNK and mediated downstream by NF-kappaB