Gene interactions and pathways from curated databases and text-mining

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ESR1 — NRF1

Text-mined interactions from Literome

Mattingly et al., Mol Endocrinol 2008 : E ( 2 ) -induced NRF-1 expression was inhibited by the estrogen receptor ( ER ) antagonist ICI 182,780 and actinomycin D but not by phosphoinositide-3 kinase and MAPK inhibitors, indicating a genomic mechanism of E ( 2 ) regulation of NRF-1 transcription
Mattingly et al., Arch Toxicol 2012 : Here we tested the hypothesis that diesel exhaust particulate extracts ( DEPEs ), prepared from a truck run at different speeds and engine loads, would inhibit genomic estrogen receptor activation of nuclear respiratory factor-1 (NRF-1) transcription in human umbilical vein endothelial cells ( HUVECs )