Gene interactions and pathways from curated databases and text-mining

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NOX4 — TGFBR1

Text-mined interactions from Literome

Murillo et al., Biochem J 2007 : Results indicate that DPI ( diphenyleneiodonium ) and apocynin, two NOX ( NADPH oxidase ) inhibitors, and SB431542, an inhibitor of the TbetaR-I ( TGF-beta receptor I ), block up-regulation of EGFR ligands and Akt activation
Boudreau et al., Free Radic Biol Med 2012 : Expression of a constitutively active TGF-beta receptor type I significantly increased Nox4 promoter activity, mRNA and protein expression, and ROS generation