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NOX4 — TXN
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Wu et al., J Endocrinol Invest 2013
:
Trx and PPAR? were significantly decreased, and Txnip expression and
NADPH oxidase activity markedly
increased , in the D and T groups compared to the C group
Nordberg et al., J Biol Chem 1998
:
The immunostimulatory dinitrohalobenzene compound 1-chloro-2, 4-dinitrobenzene ( DNCB ) irreversibly inhibits mammalian
thioredoxin reductase (TrxR) in the presence of NADPH,
inducing an
NADPH oxidase activity in the modified enzyme ( Arnér, E. S. J., Björnstedt, M., and Holmgren, A. ( 1995 ) J. Biol. Chem. 270, 3479-3482 )