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BCCIP — TP53

Text-mined interactions from Literome

Meng et al., Cell cycle (Georgetown, Tex.) 2004 : We further show that the regulation of p21 expression by BCCIP is dependent on p53, and BCCIP regulates p53 transcription activity
Meng et al., J Biol Chem 2007 (Neoplasms) : In this report, we show that BCCIP , a BRCA2 and CDKN1A interacting protein, is required for the transactivation activity of wild type p53 ... These data demonstrate a critical role of BCCIP in maintaining the transactivation activity of wild type p53 and further suggest down-regulation of BCCIP as a novel mechanism to impair the p53 function in cells harboring wild type p53
Huang et al., PloS one 2012 (Ataxia...) : With in vitro neural spheroid cultures, BCCIP deficiency impaired neural progenitor 's self-renewal capability, and spontaneously activated p53