Gene interactions and pathways from curated databases and text-mining

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IFNG — OAS3

Text-mined interactions from Literome

Bruchelt et al., Eur J Clin Chem Clin Biochem 1992 : In contrast, interferon gamma ( 2-4 x 10 ( 6 ) IU ) caused only a small induction of 2'-5'-oligoadenylate synthetase
Pozharskaya et al., J Gen Virol 2004 : Both IFN-alpha and IFN-gamma induced expression of the antiviral proteins double stranded RNA activated protein kinase ( PKR ) and 2'5'-oligoadenylate synthetase ( 2'5'-OAS ) in HHV-8 infected BCBL-1 cells
Austin et al., J Interferon Cytokine Res 2006 : Involvement of OAS and PKR in IFN-gamma induced anti-herpes simplex virus-1 ( HSV-1 ) pathways has not been reported previously, but IFN-gamma induces OAS and PKR when other viruses invade the nervous system ... The aim of the current study was to determine if the absence of intact OAS and PKR antiviral pathways affects the antiviral activity of IFN-gamma during acute HSV-1 infection within the trigeminal ganglia ( TG )
Smith et al., J Interferon Res 1991 : Trypsin inhibitors and GC also inhibited induction of intracellular 2',5'-oligoadenylate ( 2-5A ) synthetase by IFN-gamma
Gribaudo et al., Eur J Immunol 1990 : We have examined the mechanisms by which interferon (IFN)-gamma and IFN-alpha regulate the expression of 2'-5'-oligoadenylate synthetase ( 2-5A synthetase ) and class I major histocompatibility complex antigens in murine T cells and in cell types of other histological origin
Schiller et al., J Biol Response Mod 1990 (Colonic Neoplasms) : To determine if a correlation could be established between this synergistic antiproliferative effect and a synergistic induction in IFN-inducible proteins, or a unique perturbation in the cell cycle, we studied the effects of IFN-beta ser and IFN-gamma , alone and in combination, on 2',5'-oligoadenylate ( 2-5A ) synthetase , indoleamine-2,3-dioxygenase (IDO), a human analogue of the murine Mx protein ( p78 ), and the phases of cell cycle
Warner et al., J Clin Invest 1989 : Immune interferon inhibits proliferation and induces 2'-5'-oligoadenylate synthetase gene expression in human vascular smooth muscle cells
Goldberg et al., J Cell Biol 1989 : The genetic analysis indicated that IFN-alpha and IFN-gamma regulate the induction of the dsRNA dependent P1/eIF-2 alpha protein kinase and 2',5'-oligoadenylate synthetase enzymatic activities via different pathways
Zucca et al., G Batteriol Virol Immunol 1989 : The lack of antiviral activity was confirmed at the biochemical level by the finding that 2',5 ' oligoadenylate synthetase activity is not induced in T cells by IFN gamma only
Zucca et al., J Biol Regul Homeost Agents 1988 : IFN gamma , unlike IFN alpha, did not promote the antiviral state in these cells, or induce the activity of 2'-5 ' oligoadenylate synthetase
Kawanishi et al., J Med Virol 1995 : These results suggest that tumor necrosis factor-alpha and interferon-gamma inhibit hepatitis B virus replication by blocking some step in reverse transcription and that the 2',5'-oligoadenylate synthetase is not involved in the mechanism underlying the inhibition by these two cytokines
Marin et al., J Interferon Cytokine Res 1996 : IL-6 did not potentiate IFN-gamma induced 2'-5'-oligoadenylate synthetase activity