Gene interactions and pathways from curated databases and text-mining

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NOTCH3 — PROX1

Text-mined interactions from Literome

Kang et al., Blood 2010 : We found that Notch signal down-regulates Prox1 and COUP-TFII through Hey1 and Hey2 and that activated Notch receptor suppresses the lymphatic phenotypes and induces the arterial cell fate
Yoo et al., PLoS Pathog 2012 (Herpesviridae Infections) : Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus ... Here, we report that IL3 receptor alpha ( IL3Ra ) and NOTCH play integral roles in the host cell type-specific regulation of PROX1 by KSHV