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CXCL3 — INS
Text-mined interactions from Literome
Wurm et al., Cytokine 2008
:
Insulin induces monocytic
CXCL8 secretion by the mitogenic signalling pathway ... Inhibition of the phosphatidylinositol 3-kinase by wortmannin or the mammalian target of rapamycin by rapamycin did not influence
insulin mediated
CXCL8 induction ... In contrast, blockage of the ERK-specific MAP kinase MEK with PD98059, that prevents phosphorylation of ERK1/ERK2, abrogated
insulin induced
CXCL8 release in primary monocytes
Farquharson et al., Mol Biol Rep 2012
(Colonic Neoplasms...) :
In contrast to leptin,
insulin significantly reduced CCL20 and CXCL11 and
increased CXCL3 expression