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PTEN — RAC1
Text-mined interactions from Literome
Kim et al., Blood 2002
:
PTEN controls immunoreceptor ( immunoreceptor tyrosine based activation motif ) signaling and the activation of
Rac
Wu et al., Carcinogenesis 2007
(Bone Neoplasms...) :
Constitutively active Rac1 but not focal adhesion kinase or Cdc42 could rescue cells from the inhibitory effect of PTEN on cell migration and
PTEN induction was observed to
inhibit Rac1 activation in response to calvaria conditioned medium
Malchinkhuu et al., Mol Biol Cell 2009
(Glioma) :
The expression of tumor suppressor
phosphatase and tensin homolog deleted on chromosome 10 ( PTEN ) is
required for the inhibitory ISO induced and Rap1B mediated actions on the migration,
Rac1 activation, and Akt activation in response to LPA