Gene interactions and pathways from curated databases and text-mining

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BPI — IL8

Text-mined interactions from Literome

Dentener et al., J Immunol 1993 : LBP was shown to enhance LPS induced TNF-alpha, IL-6, and IL-8 release by mononuclear phagocytic cells, whereas BPI inhibited the release of these cytokines
Dentener et al., J Infect Dis 1997 : In addition, the inflammatory mediator tumor necrosis factor (TNF)-alpha potently activated PMNL in whole blood, via TNF receptor p55, to release BPI, whereas interleukin (IL)-1, IL-8 , platelet activating factor, and C5a were poor inducers of BPI release