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IL3 — SPP1

Text-mined interactions from Literome

Lin et al., Mol Cell Biol 2000 : Antibody blocking experiments revealed that OPN produced as a result of IL-3 or GM-CSF signaling was secreted into the medium and, through binding to its cell surface receptor, CD44, contributed to the survival promoting activities of these two cytokines
Lin et al., J Biol Chem 2001 : We have recently demonstrated that the gene encoding the osteopontin (OPN) protein is activated both by interleukin-3 and granulocyte-macrophage colony stimulating factor signaling pathways and that, through binding to the cell surface receptor CD44, OPN contributes to the survival activities of interleukin (IL)-3 and GM-CSF ( Lin, Y.-H., Huang, C.-J., Chao, J.-R., Chen, S.-T., Lee, S.-F., Yen, J. J.-Y., and Yang-Yen, H.-F
Koguchi et al., Infect Immun 2002 (AIDS-Related Opportunistic Infections) : Penicillium marneffei causes osteopontin mediated production of interleukin-12 by peripheral blood mononuclear cells
Himeno et al., J Bone Miner Res 2002 (Ossification, Heterotopic) : In primary culture of Cbfa1-/- chondrocytes, transforming growth factor (TGF) beta1, platelet derived growth factor ( PDGF ), interleukin (IL)-1beta , and thyroid hormone ( T3 ) induced osteopontin and MMP-13 expression
Mas et al., Mult Scler 2007 (Genetic Predisposition to Disease...) : OPN enhances the production of the pro-inflammatory cytokines, interleukin-12 and interferon-gamma, while reducing interleukin-10 levels
Diao et al., Cytokine 2012 (Drug-Induced Liver Injury...) : Osteopontin regulates interleukin-17 production in hepatitis
Singh et al., J Biol Chem 1995 : In vitro, interleukin-1 beta and interferon-gamma increased osteopontin mRNA levels in CMEC as well as NOS2 expression in both CMEC and cardiac myocytes