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CFTR — NPY6R

Text-mined interactions from Literome

Dahan et al., Pflugers Arch 2001 (Cystic Fibrosis) : Phosphatases that deactivate CFTR have yet to be identified definitively at the molecular level, however CFTR is regulated by a membrane bound form of protein phosphatase-2C ( PP2C ) in several cell types ... Understanding the regulation of CFTR by PP2C is a priority due to its potential as a target for pharmacotherapies in the treatment of cystic fibrosis
Fischer et al., Pflugers Arch 1998 : We propose that in order to regulate CFTR in an intact cell, PP2B may require a selective subcellular localization to become active
Luo et al., Am J Physiol 1998 : Adding PP2A, PP2C , or alkaline phosphatase to excised patches reduced CFTR channel activity by > 90 % but did not abolish it completely