Gene interactions and pathways from curated databases and text-mining

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CD4 — MBP

Text-mined interactions from Literome

Matyszak et al., Eur J Immunol 1999 : Resting and IFN-gamma activated microglia were unable to activate naive and primed myelin basic protein (MBP)-specific CD4 ( + ) T cells in the presence of MBP and encephalomyelitic MBP Ac1-11 peptide
Laplaud et al., Brain 2004 (Multiple Sclerosis) : Cells bearing the TCR transcripts with altered CDR3-LD were sorted and studied for CD4 or CD8 phenotype, cytokine transcript accumulation and response to human myelin basic protein (MBP)
Saresella et al., J Neuroimmunol 2005 (Acute Disease...) : Results showed that mitogen stimulated apoptosis was comparable among patients and controls, whereas MBP stimulated CD4+ and CD8+ 7-AAD+ and 7-AAD+ Fas+ cell ( apoptotic cells ) were significantly reduced in AMS patients
Harp et al., Eur J Immunol 2010 (Multiple Sclerosis, Relapsing-Remitting) : Notwithstanding the fact that the phenotypic parameters that promote efficient Ag presentation were observed to be similar between RRMS and HD memory B cells, a corresponding capability to elicit CD4 ( + ) T-cell proliferation in response to myelin basic protein and myelin oligodendrocyte glycoprotein was not observed in HD memory B cells