Gene interactions and pathways from curated databases and text-mining

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NOS3 — PARP1

Text-mined interactions from Literome

Hassa et al., J Biol Chem 2001 : Finally, we showed that PARP-1 is activating the natural inducible nitric-oxide synthase and P-selectin promoter in a kappa B-dependent manner upon stimulation of the cells with inflammatory stimuli or cotransfection of p65
Nakajima et al., J Biol Chem 2004 (Inflammation) : PARP-1 inhibitors and the antisense RNA for PARP-1 mRNA suppressed lipopolysaccharide (LPS) induced expression of tumor necrosis factor-alpha and inducible nitric-oxide synthase , suggesting that PARP-1 activity has a critical role in synthesis
von Lukowicz et al., Cardiovasc Res 2008 (Atherosclerosis...) : PARP inhibition or PARP1 deletion reduced PARP activity and diminished expression of inducible nitric oxide synthase , vascular cell adhesion molecule-1, and P- and E-selectin