Gene interactions and pathways from curated databases and text-mining

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CFL1 — PTEN

Text-mined interactions from Literome

Serezani et al., Science signaling 2012 (Candidiasis) : PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2 mediated inhibition of phagocytosis of fungi ... PGE ( 2 ) -dependent activation of cofilin-1 was mediated by the protein phosphatase activity of PTEN ( phosphatase and tensin homolog deleted on chromosome 10 ), with which it directly associated
Vitolo et al., Oncogene 2013 : Loss of PTEN induces microtentacles through PI3K independent activation of cofilin ... PTEN loss and PI3K activation also caused differential activation of the cofilin regulators, LIM-kinase1 ( LIMK ) and Slingshot-1L ( SSH )