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IL1B — NFKBIB
Text-mined interactions from Literome
Jiang et al., Arterioscler Thromb Vasc Biol 2001
:
IkappaBbeta , but not IkappaBalpha degradation,
induced by
IL-1beta was markedly attenuated when ERK activation was inhibited and could be partially responsible for the persistent NF-kappaB activation
Agarwal et al., FASEB J 2003
:
TENS-L is a potent inhibitor of interleukin
(IL)-1 beta induced
I-kappaBbeta degradation and prevents dissociation of NF-kB from cytoplasmic complexes and thus its nuclear translocation
Xu et al., Am J Physiol Cell Physiol 2006
(MAP Kinase Signaling System) :
In cultured rat VSMCs,
IL-1beta activated ERK and induced degradation of both IkappaBalpha and
IkappaBbeta , which was associated with nuclear translocation of both ribosomal S6 kinase (RSK)1 and NF-kappaB p65
Nam et al., PloS one 2009
(Inflammation) :
This suppression of NOS2 by DCS correlates with the attenuation of the NF-kappaB signaling pathway as measured by
IL-1beta induced phosphorylation of the inhibitor of kappa B (IkappaB)-alpha, degradation of IkappaB-alpha and
IkappaB-beta , and subsequent nuclear translocation of NF-kappaB p65