◀ Back to IFNB1

IFNB1 — TIRAP

Text-mined interactions from Literome

Yamamoto et al., J Immunol 2002 : Furthermore, TRIF, but neither MyD88 nor TIRAP , activated the IFN-beta promoter
Oshiumi et al., J Biol Chem 2003 : Although MyD88 and Mal/TIRAP adapters functions downstream of TLR4, DC maturation and IFN-beta induction are independent of MyD88 and Mal/TIRAP
Andreakos et al., Blood 2004 : In contrast, in macrophages neither MyD88, Mal/TIRAP, nor I kappa B kinase 2 (IKK2) are required for NF-kappa B activation or tumor necrosis factor alpha (TNF alpha), IL-6, or IL-8 production, although Mal/TIRAP is still involved in the production of interferon beta (IFN beta)
Sengupta et al., J Immunol 2010 : This effect of TcpB is mediated through its box 1 region and has no effect on other TLR adapter proteins such as MyD88 or TIR-domain containing adapter protein inducing IFNbeta
Liu et al., J Immunol 2010 : Overexpression of zebrafish Tirap in HEK293T cells did not activate NF-kappaB and IFN-beta , but slightly activated NF-kappaB in carp leukocyte cells