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C1QA — TNF

Text-mined interactions from Literome

Lurton et al., Exp Lung Res 1999 : Regulation of human lung fibroblast C1q-receptors by transforming growth factor-beta and tumor necrosis factor-alpha
Bajtay et al., Eur J Immunol 2000 : Studying the functional consequences of the interaction, we found that the release of TNF-alpha from Mphi is induced by C1q but not by MBL
Csomor et al., Mol Immunol 2007 : Immobilized C1q induced maturation of MDCs and enhanced secretion of IL-12 and TNF-alpha , moreover, elevated their T-cell stimulating capacity
Arora et al., Cytokine 2009 : In the presence of TNF , both mAbs bound C1q in in vitro assays, but etanercept did not bind C1q under any conditions
Fraser et al., J Neurochem 2010 (Blister) : Microglia added to C1q coated wells or fed apoptotic neurons or neuronal blebs coated with C1q suppressed the lipopolysaccharide induced production of proinflammatory cytokines interleukin (IL)-1alpha, IL-1beta, IL-6 and TNF-alpha , while the presence of C1q enhanced levels of the chemokine MCP-1/CCL2
Leu et al., Immunobiology 1993 : Inhibitor of C1q secretion suppresses the macrophage response to lipid A for nitric oxide but not for TNF production : evidence for a role of C1q in autocrine binding of TNF ... C1q was confirmed to bind to macrophages at 4 degrees C as detected by FITC anti-C1q, F ( ab ' ) 2 and such C1q binding promoted a corresponding increased binding of PE-TNF ... Since TNF binding to DHP treated macrophages was reconstituted by the binding of exogenous C1q to the cells, it appears that C1q may be involved in the modulation of autocrine binding of TNF for subsequent generation of cytotoxic NO
Jiang et al., Cell Immunol 1996 : The role of complement subcomponent C1q in the modulation of TNF-alpha binding to L929 cells to mediate cytotoxicity and nitric oxide ( NO ) generation was investigated
Jiang et al., Scand J Immunol 1996 : In the present study, the putative role of C1q in increasing TNF-alpha binding to L929 cells to mediate cytotoxicity was explored
Bottazzi et al., J Biol Chem 1997 : The capacity to bind C1q , mediated by the pentraxin domain, is consistent with the view that PTX3, produced in tissues by endothelial cells or macrophages in response to interleukin-1 and tumor necrosis factor , may act as a local regulator of innate immunity