Gene interactions and pathways from curated databases and text-mining

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NAB2 — TNFSF10

Text-mined interactions from Literome

Wolkers et al., Blood 2012 : Enforced expression of Nab2 prevents TRAIL induction after restimulation of primary helpless CD8 ( + ) T cells, and expression of a dominant negative form of Nab2 in helped CD8 ( + ) T cells impairs their secondary proliferative response that is reversible by TRAIL blockade
Balzarolo et al., Eur J Immunol 2012 : Furthermore, PI3K signaling is required for NAB2 mediated TRAIL expression
Balzarolo et al., Immunol Lett 2013 : Provided that TRAIL plays a key role in NK cell cytotoxicity towards infected and tumor cells, we investigated whether NAB2 also mediates TRAIL expression in human NK cells, and if so through which mechanisms