Gene interactions and pathways from curated databases and text-mining

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CCR4 — TNF

Text-mined interactions from Literome

Zhao et al., J Oral Pathol Med 2002 (Lichen Planus) : TNF-alpha stimulated CCR1, CCR4 and CCR5 mRNA expression in the same cell line
Croitoru-Lamoury et al., Glia 2003 : Moreover, TNFalpha and IL-1beta significantly increase BOB/GPR15, CCR2 , and V28/CX3CR1 mRNA levels in both models
Vestergaard et al., Exp Dermatol 2004 (Dermatitis, Atopic) : Performing immunohistochemical stainings, reverse-transcription polymerase chain reaction ( RT-PCR ), and Western blotting, we found that TNF-a induced CCR4 mRNA production, but that stimulated as well as non stimulated keratinocytes expressed CCR4
Ponte et al., Stem Cells 2007 : TNFalpha increases CCR2, CCR3 , and CCR4 expression ( as opposed to that of CXCR4 ), together with RANTES membrane binding
Catley et al., IDrugs 2010 (Asthma...) : This conference report highlights selected presentations on mAb treatments for asthma, including targeting IL-5, IL-13, IL-9 and TNFa , CCR3 inhibitors , histamine H4 receptor inhibition, novel mouse models of COPD and inhaled antisense asthma therapies