Melkoumian et al., Cancer Res 2005
(Breast Neoplasms) :
In addition, FIP200 significantly induced p21 promoter activity in MCF-7 cells and this response was abolished upon deletion of p53 binding sites within p21 promoter
Martin et al., Mol Cell Biol 2008
:
Conversely, FIP200 enhances the transcriptional activation of the p21 promoter by PIASy whereas PIASy transcription activity is severely reduced upon FIP200 depletion by RNA interference