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IL4 — MYLIP
Text-mined interactions from Literome
Stanczyk et al., Arthritis Rheum 2008
(Arthritis, Rheumatoid) :
Constitutive expression of both miR-155 and miR-146a was higher in RASFs than in those from patients with osteoarthritis ( OA ), and expression of
miR-155 could be further
induced by TNFalpha,
interleukin-1beta , lipopolysaccharide, poly ( I-C ), and bacterial lipoprotein
Maurer et al., Arthritis Rheum 2010
(Scleroderma, Systemic) :
TGFbeta, PDGF-B, or
IL-4 reduced the levels of
miR-29a in normal fibroblasts to those seen in SSc fibroblasts
Majid et al., Cancer 2010
(Neoplasm Invasiveness...) :
In this study, the authors demonstrated that
miRNA-205 (miR-205) induced the expression the
interleukin ( IL ) tumor suppressor genes IL24 and IL32 by targeting specific sites in their promoters
Thapa et al., AIDS 2012
(HIV Infections...) :
Moreover,
miR-21 is overexpressed in activated B cells and can be
induced by
interleukin 4 alone, or with CD40 or immunoglobulin M co-stimulation, and lipopolysaccharides, suggesting that miR-21 may help maintain B-cell hyperactivation, contributing to lymphomagenesis
Rückerl et al., Blood 2012
:
In vitro experiments demonstrated that
miR-378-3p was specifically
induced by
IL-4 and revealed the IL-4-receptor/PI3K/Akt signaling pathway as a target
Kelada et al., PLoS Pathog 2013
(Inflammation...) :
In contrast,
IL-4 regulated
miR-182 and cMaf in Th2 associed Treg cells, which mitigated IL-2 secretion, in part through repression of IL2 promoting genes
Kopriva et al., PloS one 2013
:
Overexpression of miR-210 in CTBs decreased STAT6 and IL-4 while inhibition of
miR-210 increased STAT6 and
IL-4