Gene interactions and pathways from curated databases and text-mining

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SLC22A3 — SPP1

Text-mined interactions from Literome

Saika et al., Lab Invest 2007 : OPN is required for activation of Smad2/3 signal in an injured lens epithelium and lens cell EMT
Li et al., J Am Coll Surg 2013 (Adenocarcinoma...) : Analysis through quantitative polymerase chain reaction demonstrated APT inhibition of OPN in MDA-MB-231 cells caused a decrease in EMT-TF expression ( MDA-MB-231 vs MDA-MB-231+APT : *Twist ddCT : 1.0 vs 0.07 ; *Snail ddCT : 1.0 vs 0.11 ; *Slug ddCT : 1.0 vs 0.11 ; *p < 0.001 )