Gene interactions and pathways from curated databases and text-mining

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CDK6 — MYC

Pathways - manually collected, often from reviews:

  • KEGG Small cell lung cancer: Complex of MAX-MYC → Complex of CCND1-CDK4-CDK6 (gene expression, expression)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Mateyak et al., Mol Cell Biol 1999 : c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points
Amati et al., Frontiers in bioscience : a journal and virtual library 1998 : Cyclin D/CDK4 and CDK6 may conceivably also be activated by Myc , but the circumstances in which this occurs remain to be explored