◀ Back to WNT3A
BMP2 — WNT3A
Text-mined interactions from Literome
Rawadi et al., J Bone Miner Res 2003
:
Moreover,
BMP-2 enhanced Wntl and
Wnt3a expression in our cells
Nakashima et al., J Biol Chem 2005
:
In contrast,
BMP-2 or Smad1/4
up-regulated Wnt3a or activated beta-catenin induced lymphoid enhancing factor 1/T cell factor dependent transcriptional activity
Dai et al., Cancer Res 2008
(Neoplasm Metastasis...) :
Transfection of C4-2B cells with axin, an inhibitor of canonical Wnt signaling, blocked
Wnt3a but not Wnt5a
induction of the
BMP promoters ... In contrast, Jnk inhibitor I blocked Wnt5a but not
Wnt3a induction of the
BMP promoters
Wang et al., Stem cell research 2009
:
Interestingly,
WNT3a stimulation of hemoangiogenic cell genesis was virtually abolished in the
presence of a
BMP inhibitor
Miura et al., Dev Biol 2010
:
These data indicate that
BMP signaling in the epiblast
induces Wnt3 and
Wnt3a expression to maintain WNT signaling in the VE, resulting in downregulation of Dkk1 to establish the anterior expression domain
Olivares-Navarrete et al., Acta Biomater 2011
:
Wnt5a, but not
Wnt3a ,
increased MG63 cell differentiation and
BMP2 and BMP4 proteins, suggesting Wnt5a promotes osteogenic differentiation through production of BMPs. Effects of exogenous and endogenous Wnt5a were synergistic with surface microstructure, suggesting the response also depends on cell maturation state
Zhang et al., Bone 2013
:
Activation of Wnt signaling by
Wnt3a or overexpression of ß-catenin/TCF4 both
stimulated BMP2 transcription at promoter and mRNA levels