Gene interactions and pathways from curated databases and text-mining

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CPD — PRL

Text-mined interactions from Literome

Too et al., Endocrinology 2001 (Neoplasms) : CPD-N expression ( 7.5-kb messenger RNA ) was stimulated by PRL ( 10 ng/ml ) and/or by interleukin-2 ( 24 U/ml ) in Nb2-11C and Nb2-Sp cells
Abdelmagid et al., Endocrinology 2008 (Breast Neoplasms) : We have reported that prolactin (PRL) regulated CPD mRNA levels in MCF-7 breast cancer cells ... This study examined PRL/17beta-estradiol ( E2 ) regulation of CPD/CPM expression, and the role of CPD in NO production for survival of MCF-7 cells ... PRL/E2 increased CPD mRNA levels by 3- to 5-fold but had no effect on CPM ... In summary, PRL/E2 induced cell-surface CPD released Arg from extracellular substrates, increased intracellular NO, promoted survival and inhibited apoptosis of MCF-7 cells
Thomas et al., Prostate 2012 (Adenocarcinoma...) : This study determined the effects of testosterone ( T ) and prolactin (PRL) on CPD expression, and the role ( s ) of CPD in NO production and survival of prostate cancer ( PCa ) cells ... The effects of PRL/T on CPD/NO levels in PC-3, MDA-PCa-2b, and 22Rv1 cells were also evaluated