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GNLY — IL15

Text-mined interactions from Literome

Ma et al., J Immunol 2002 : CD8 T cell mediated killing of Cryptococcus neoformans requires granulysin and is dependent on CD4 T cells and IL-15 ... Furthermore, IL-15 was both necessary and sufficient for granulysin up-regulation in CD8 T cells
Hogg et al., J Leukoc Biol 2009 : Induction of granulysin in CD8+ T cells by IL-21 and IL-15 is suppressed by human immunodeficiency virus-1 ... Using primary human CD8+ T cells, in this study, we identify IL-21 as a strong inducer of granulysin, demonstrate that IL-21 and IL-15 activate granulysin expression within CD8+ CD45RO+ T cells, and establish a role for Jak/STAT signaling in the regulation of granulysin within CD8+ T cells
Hogg et al., Tuberculosis (Edinb) 2011 (HIV Infections) : Activation of NK cell granulysin by mycobacteria and IL-15 is differentially affected by HIV ... Infection of PBMC with HIV-1 suppresses NK cell induction of granulysin by IL-15 , but does not impair activation by BCG