Obata et al., Neuroscience 2004
(Pain...) :
Therefore, we suggest that after inflammation near the cell body, NGF synthesized within the nerve root and DRG induces BDNF expression through trkA receptors and intracellular ERK-MAPK Doya et al., Spine (Phila Pa 1976) 2005
(Wounds, Nonpenetrating) :
ERK is activated by phosphorylation in the DRG and spinal cord by noxious stimuli, which are related to pain hypersensitivity
Kato et al., Neurosci Res 2007
:
Co-culture studies suggested that dorsal root ganglion ( DRG ) activated ERK in the dorsal horn ... Brain derived neurotrophic factor (BDNF) activated ERK in the dorsal horn, and anti-BDNF blocked the DRG induced ERK activation ... These results suggest roles of BDNF in the DRG induced ERK activation in the embryonic dorsal horn