Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MAP3K13

Text-mined interactions from Literome

Bloem et al., J Mol Cell Cardiol 2001 (Cardiomegaly...) : When expressed in cardiac myocytes, MLK7 activated SAPK/JNK1, and ERK and p38 to a lesser extent
Chadee et al., Proc Natl Acad Sci U S A 2006 : Thus, MLK3 is part of a multiprotein complex and is required for ERK activation
Kovalenko et al., Am J Physiol Gastrointest Liver Physiol 2012 (Intestinal Diseases...) : MLK inhibition reduced ERK and JNK, but not p38, signaling in Caco-2 cells
Hebron et al., Br J Haematol 2013 (Multiple Myeloma...) : In myeloma tumour cells, MAP3K8 acts as mitogen induced MAP3K in mitosis and is required for TNFa mediated ERK activation