Gene interactions and pathways from curated databases and text-mining

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CD79A — SMAD3

Text-mined interactions from Literome

Park et al., Eur J Immunol 2001 (Lymphoma, B-Cell) : Smad3 and Smad4 mediate transforming growth factor-beta1 induced IgA expression in murine B lymphocytes ... Finally, in the presence of TGF-beta1, overexpression of Smad3/4 selectively increases both surface IgA expression and IgA production
Park et al., Eur J Immunol 2003 : We have shown previously that Smad3 and Smad4 mediate TGF-beta1 induced IgA expression ... Overexpression of Runx3 and Smad3/4 increased IgA secretion by both cell types in response to TGF-beta1
McKarns et al., Int Immunopharmacol 2003 : Concentration dependent bifunctional effect of TGF-beta 1 on immunoglobulin production : a role for Smad3 in IgA production in vitro ... Moreover, stimulation of IgA by TGF-beta(1) was abrogated in LPS sensitized Smad3 ( Exon8-/- ) splenocytes suggesting an additional role for Smad3 in regulating IgA production in vitro
Park et al., Eur J Immunol 2005 : Smad3/4 , Runx3 and p300 mediate TGF-beta1 induced germ-line ( GL ) alpha transcription leading to IgA expression
Li et al., Int Urol Nephrol 2010 (Glomerulonephritis, IGA) : When these findings are considered together, it is of interest to explore how Arkadia and Smad signaling affect TGF-ß ( 1 ) -induced IgA expression in IgAN