Gene interactions and pathways from curated databases and text-mining

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PTGS2 — SMAD3

Text-mined interactions from Literome

Aoki et al., Am J Physiol Cell Physiol 2007 : Moreover, dominant negative Smad2/3 expression attenuated the expression of COX-2 and alpha-SMA enhanced by IL-1beta and IL-6
Neil et al., Carcinogenesis 2008 : Moreover, stable Cox-2 expression in normal MECs stimulated their invasion, EMT and anchorage independent growth and inhibited their activation of Smad2/3 by TGF-beta